The didemethyl metabolite of escitalopram (S-DDCT) is typically present at or below quantifiable concentrations. Escitalopram and S-DCT exhibit linear and dose-proportional pharmacokinetics following single or multiple doses in the mg/day dose range. Adolescents, elderly individuals and patients with hepatic. These analyses revealed no clinically important changes in laboratory test parameters associated with Lexapro treatment. ECG Changes. Electrocardiograms from Lexapro (N=) and placebo (N=) groups were compared with respect to outliers defined as subjects with QTc changes over 60 msec from baseline or.
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Test Name, Escitalopram, Blood. Test Includes, Citalopram / Escitalopram. Compound Synonym(s), Celexa®/Lexapro®. Purpose, Therapeutic Drug Monitoring; This test is New York State approved. Category, Antidepressant. Method(s), High Performance Liquid Chromatography/ TandemMass Spectrometry (LC-MS/MS).Test Name: Escitalopram, Blood. Following a single oral dose (20 mg tablet or solution) of escitalopram, peak blood levels occur at about 5 hours. Absorption of escitalopram is not affected by food. The absolute bioavailability of citalopram is about 80% relative to an intravenous dose, and the volume of distribution of citalopram is about 12 L/kg.
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